5if7: Difference between revisions

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-'''Unreleased structure'''
-The entry 5if7 is ON HOLD  until Paper Publication
+==Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-279 N-[(4-chlorophenyl)methyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine==
+<StructureSection load='5if7' size='340' side='right' caption='[[5if7]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
-Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID)
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5if7]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IF7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IF7 FirstGlance]. <br>
-Description: Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-279 N-[(4-chlorophenyl)methyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6AY:N-[(4-CHLOROPHENYL)METHYL]-1-METHYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>6AY</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iuj|4iuj]], [[5ieq|5ieq]], [[5if2|5if2]], [[5if5|5if5]], [[5if8|5if8]], [[5ifb|5ifb]], [[5ifc|5ifc]]</td></tr>
-[[Category: Seattle Structural Genomics Center For Infectious Disease (Ssgcid)]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5if7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5if7 OCA], [http://pdbe.org/5if7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5if7 RCSB], [http://www.ebi.ac.uk/pdbsum/5if7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5if7 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/PA_I33A0 PA_I33A0]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication.
+__TOC__
+</StructureSection>
+[[Category: Structural genomic]]
+[[Category: Flu]]
+[[Category: Fragment screening]]
+[[Category: Niaid]]
+[[Category: Ssgcid]]
+[[Category: Std nmr]]
+[[Category: Viral protein]]