IGF1: Difference between revisions
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<StructureSection load='1gzr' size='340' side='right' caption='Structural basis for IGF1 protein with N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE ligand' scene=''> | <StructureSection load='1gzr' size='340' side='right' caption='Structural basis for IGF1 protein with N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE ligand' scene=''> | ||
Insulin is a very important endocrine protein. Indeed, it is the only hypoglycemic hormone of the human body. This protein is secreted in the beta cells of the Langerhans’ islet in the pancreas and takes part in the glycogenesis. This molecule helps the transportation of glucose into the cells, thus reducing the blood sugar rate, contrary to glucagon. | '''Insulin''' is a very important endocrine protein. Indeed, it is the only hypoglycemic hormone of the human body. This protein is secreted in the beta cells of the Langerhans’ islet in the pancreas and takes part in the glycogenesis. This molecule helps the transportation of glucose into the cells, thus reducing the blood sugar rate, contrary to glucagon. | ||
Insulin also has a huge effect on growth and thereby has a lot of structural similarities with its main associated growth factor: IGF1, aka somatomedin. Both share lots of properties thanks to their 60% similarity. | Insulin also has a huge effect on growth and thereby has a lot of structural similarities with its main associated growth factor: IGF1, aka somatomedin. Both share lots of properties thanks to their 60% similarity. | ||
IGF1 is a peptidic hormone of 69 amino acids which is secreted by the liver. | IGF1 is a peptidic hormone of 69 amino acids which is secreted by the liver. | ||