5hkl: Difference between revisions
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==Crystal structure of Mycobacterium tuberculosis H37Rv orotate phosphoribosyltransferase in complex with inorganic phosphate== | |||
<StructureSection load='5hkl' size='340' side='right' caption='[[5hkl]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5hkl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HKL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HKL FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hkl OCA], [http://pdbe.org/5hkl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hkl RCSB], [http://www.ebi.ac.uk/pdbsum/5hkl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hkl ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PYRE_MYCTU PYRE_MYCTU]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Orotate phosphoribosyltransferase]] | |||
[[Category: Bolognesi, G]] | [[Category: Bolognesi, G]] | ||
[[Category: Donini, S]] | [[Category: Donini, S]] | ||
[[Category: Rizzi, M]] | [[Category: Rizzi, M]] | ||
[[Category: De novo pyrimidine nucleotide synthesis]] | |||
[[Category: Inorganic phosphate complex]] | |||
[[Category: Oprt]] | |||
[[Category: Transferase]] |