5g4x: Difference between revisions
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The | ==The crystal structure of the SHANK3 N-terminus== | ||
<StructureSection load='5g4x' size='340' side='right' caption='[[5g4x]], [[Resolution|resolution]] 2.17Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5g4x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G4X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G4X FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5g4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g4x OCA], [http://pdbe.org/5g4x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g4x RCSB], [http://www.ebi.ac.uk/pdbsum/5g4x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g4x ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/SHAN3_RAT SHAN3_RAT]] Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Barsukov, I]] | [[Category: Barsukov, I]] | ||
[[Category: Zacharchenko, T]] | [[Category: Zacharchenko, T]] | ||
[[Category: Integrin]] | |||
[[Category: Ra]] | |||
[[Category: Shank3]] | |||
[[Category: Structural protein]] | |||
Revision as of 02:39, 26 January 2017
The crystal structure of the SHANK3 N-terminusThe crystal structure of the SHANK3 N-terminus
Structural highlights
Function[SHAN3_RAT] Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction. |
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