Rho GTPase activating protein: Difference between revisions

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<StructureSection load='1ow3' size='340' side='right' caption='Human RhoGAP 1 (grey) complex with RhoA (green), GDP, MgF3 and Mg+2 ions (PDB code [[1ow3]])' scene=''>
<StructureSection load='1ow3' size='340' side='right' caption='Human RhoGAP 1 (grey) complex with RhoA (green), GDP, MgF3 and Mg+2 ions (PDB code [[1ow3]])' scene=''>
 
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== Function ==
== Function ==
'''Rho GTPase activating protein''' (RhoGAP) are one of the main classes of Rho GTPase regulators that are crucial in cell cytoskeletal organization, growth, differentiation, neuronal development and synaptic functions<ref>PMID:12480336</ref>.  RhoGAPs contain a RhoGAP domain.
'''Rho GTPase activating protein''' (RhoGAP) are one of the main classes of Rho GTPase regulators that are crucial in cell cytoskeletal organization, growth, differentiation, neuronal development and synaptic functions<ref>PMID:12480336</ref>.  RhoGAPs contain a RhoGAP domain.

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Michal Harel, Joel L. Sussman, Alexander Berchansky