Tau protein: Difference between revisions

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Protein aggregation also exists in patients suffering from Parkinson’s disease, specifically within the substantia nigra of the midbrain <ref name="Ross">PMID: 15272267</ref>. Immunohistochemical studies reveal that abnormally phosphorylated tau proteins are partially involved in the development of Lewy bodies, protein aggregates, within the substantia nigra <ref name="Ishizawa">PMID: 12722831</ref>. Lewy bodies may be involved in the neurodegeneration of dopaminergic neurons within this area <ref name="Ross"/>.   
Protein aggregation also exists in patients suffering from Parkinson’s disease, specifically within the substantia nigra of the midbrain <ref name="Ross">PMID: 15272267</ref>. Immunohistochemical studies reveal that abnormally phosphorylated tau proteins are partially involved in the development of Lewy bodies, protein aggregates, within the substantia nigra <ref name="Ishizawa">PMID: 12722831</ref>. Lewy bodies may be involved in the neurodegeneration of dopaminergic neurons within this area <ref name="Ross"/>.   


==3D Structures of protein tau==
==3D Structures of tau protein==


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Madelyn Kasprzak, Michal Harel, Jaime Prilusky, Alexander Berchansky