3u39: Difference between revisions
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==Crystal | ==Crystal Structure of the apo Bacillus Stearothermophilus phosphofructokinase== | ||
<StructureSection load='3u39' size='340' side='right' caption='[[3u39]], [[Resolution|resolution]] 2.79Å' scene=''> | <StructureSection load='3u39' size='340' side='right' caption='[[3u39]], [[Resolution|resolution]] 2.79Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3u39]] is a 4 chain structure | <table><tr><td colspan='2'>[[3u39]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U39 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U39 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6-phosphofructokinase 6-phosphofructokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.11 2.7.1.11] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6-phosphofructokinase 6-phosphofructokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.11 2.7.1.11] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u39 OCA], [http://pdbe.org/3u39 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3u39 RCSB], [http://www.ebi.ac.uk/pdbsum/3u39 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3u39 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u39 OCA], [http://pdbe.org/3u39 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3u39 RCSB], [http://www.ebi.ac.uk/pdbsum/3u39 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3u39 ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: 6-phosphofructokinase]] | [[Category: 6-phosphofructokinase]] | ||
[[Category: Bruning, J B]] | [[Category: Bruning, J B]] | ||
[[Category: Mosser, R]] | [[Category: Mosser, R]] | ||
Revision as of 12:22, 2 January 2017
Crystal Structure of the apo Bacillus Stearothermophilus phosphofructokinaseCrystal Structure of the apo Bacillus Stearothermophilus phosphofructokinase
Structural highlights
Publication Abstract from PubMedThe crystal structure of the unliganded form of Bacillus stearothermophilus phosphofructokinase (BsPFK) was determined using molecular replacement to 2.8 A resolution (Protein Data Bank entry 3U39 ). The apo BsPFK structure serves as the basis for the interpretation of any structural changes seen in the binary or ternary complexes. When the apo BsPFK structure is compared with the previously published liganded structures of BsPFK, the structural impact that the binding of the ligands produces is revealed. This comparison shows that the apo form of BsPFK resembles the substrate-bound form of BsPFK, a finding that differs from previous predictions. Structure of the apo form of Bacillus stearothermophilus phosphofructokinase.,Mosser R, Reddy MC, Bruning JB, Sacchettini JC, Reinhart GD Biochemistry. 2012 Jan 24;51(3):769-75. Epub 2012 Jan 11. PMID:22212099[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
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