4mpv: Difference between revisions

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==Human beta-tryptase co-crystal structure with (2R,4S)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-4-hydroxy-2-(2-hydroxypropan-2-yl)-5,5-dimethyl-1,3-dioxolane-2,4-dicarboxamide==
==Human beta-tryptase co-crystal structure with (2R,4S)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-4-hydroxy-2-(2-hydroxypropan-2-yl)-5,5-dimethyl-1,3-dioxolane-2,4-dicarboxamide==
<StructureSection load='4mpv' size='340' side='right' caption='[[4mpv]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
<StructureSection load='4mpv' size='340' side='right' caption='[[4mpv]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mpu|4mpu]], [[4mpw|4mpw]], [[4mpx|4mpx]], [[4mqa|4mqa]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mpu|4mpu]], [[4mpw|4mpw]], [[4mpx|4mpx]], [[4mqa|4mqa]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptase Tryptase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.59 3.4.21.59] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tryptase Tryptase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.59 3.4.21.59] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mpv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mpv RCSB], [http://www.ebi.ac.uk/pdbsum/4mpv PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mpv OCA], [http://pdbe.org/4mpv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mpv RCSB], [http://www.ebi.ac.uk/pdbsum/4mpv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mpv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TRYB1_HUMAN TRYB1_HUMAN]] Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type (By similarity).  
[[http://www.uniprot.org/uniprot/TRYB1_HUMAN TRYB1_HUMAN]] Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type (By similarity).  
==See Also==
*[[Tryptase|Tryptase]]
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</StructureSection>
</StructureSection>

Revision as of 10:20, 23 December 2016

Human beta-tryptase co-crystal structure with (2R,4S)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-4-hydroxy-2-(2-hydroxypropan-2-yl)-5,5-dimethyl-1,3-dioxolane-2,4-dicarboxamideHuman beta-tryptase co-crystal structure with (2R,4S)-N,N'-bis[3-({4-[3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-4-hydroxy-2-(2-hydroxypropan-2-yl)-5,5-dimethyl-1,3-dioxolane-2,4-dicarboxamide

Structural highlights

4mpv is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Activity:Tryptase, with EC number 3.4.21.59
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TRYB1_HUMAN] Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type (By similarity).

See Also

4mpv, resolution 2.31Å

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