5tc1: Difference between revisions

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-'''Unreleased structure'''
-The entry 5tc1 is ON HOLD  until Paper Publication
+==In situ structures of the genome and genome-delivery apparatus in ssRNA bacteriophage MS2==
+<StructureSection load='5tc1' size='340' side='right' caption='[[5tc1]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
-Authors: Dai, X.H., Li, Z.H., Lai, M., Shu, S., Du, Y.S., Zhou, Z.H., Sun, R.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5tc1]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_ms2 Enterobacteria phage ms2] and [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TC1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TC1 FirstGlance]. <br>
-Description: In situ structures of the genome and genome-delivery apparatus in ssRNA bacteriophage MS2
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2ms2|2ms2]]</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tc1 OCA], [http://pdbe.org/5tc1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tc1 RCSB], [http://www.ebi.ac.uk/pdbsum/5tc1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tc1 ProSAT]</span></td></tr>
-[[Category: Dai, X.H]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2]] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>  [[http://www.uniprot.org/uniprot/MAT_BPMS2 MAT_BPMS2]] The maturation protein is required for the typical attachment of the phage to the side of the bacterial pili (PubMed:23810697). MP binds to sequences located toward each end of the genome, hence circularizing it (PubMed:26608810). The RNA genome-MP complex is released from the capsid upon host receptor binding (PubMed:23810697). MP enters the cell along with the viral RNA (PubMed:4551992).<ref>PMID:23810697</ref> <ref>PMID:26608810</ref> <ref>PMID:4551992</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Enterobacteria phage ms2]]
+[[Category: Enterobacterio phage ms2]]
+[[Category: Dai, X H]]
+[[Category: Du, Y S]]
+[[Category: Lai, M]]
+[[Category: Li, Z H]]
 [[Category: Shu, S]]
-[[Category: Lai, M]]
-[[Category: Zhou, Z.H]]
-[[Category: Du, Y.S]]
-[[Category: Li, Z.H]]
 [[Category: Sun, R]]
+[[Category: Zhou, Z H]]
+[[Category: Asymmetric cryoem reconstruction]]
+[[Category: Genome-capsid interaction]]
+[[Category: Genome-delivery apparatus]]
+[[Category: Ssrna genome structure]]
+[[Category: Viral protein-rna complex]]