5tql: Difference between revisions
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==Crystal structure of TIM-Barrel protein HisF-C9S== | |||
<StructureSection load='5tql' size='340' side='right' caption='[[5tql]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5tql]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TQL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TQL FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tql OCA], [http://pdbe.org/5tql PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tql RCSB], [http://www.ebi.ac.uk/pdbsum/5tql PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tql ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/HIS6_THEMA HIS6_THEMA]] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.[HAMAP-Rule:MF_01013] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bender, B J]] | |||
[[Category: Meiler, J]] | [[Category: Meiler, J]] | ||
[[Category: | [[Category: Alpha/beta barrel]] | ||
[[Category: Lyase]] | |||
[[Category: Tim barrel]] |
Revision as of 06:31, 10 December 2016
Crystal structure of TIM-Barrel protein HisF-C9SCrystal structure of TIM-Barrel protein HisF-C9S
Structural highlights
Function[HIS6_THEMA] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.[HAMAP-Rule:MF_01013] |
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