Crixivan: Difference between revisions
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==Structure== | ==Structure== | ||
Crixivan, also known as [[Indinavir]], is an antiviral compound that acts as a protease inhibitor. The <scene name='74/745991/Crixivan/2'>structure</scene> has a molecular weight of 711.875 g/mol and is very soluble in water and ethanol.<ref>Physicians Desk Reference 66th ed. PDR Network, LLC, Montvale, NJ. p. 2086 (2012)</ref> Crixivan works by specifically binding to the HIV-1 protease active site by mimicking a target substrate protein and essentially becoming “stuck” in the enzyme active site, disabling the enzyme. The pyridine ring on Crixivan conforms the molecule to the active site. The hydroxyethylene group stabilizes the molecule and prevents cleavage. | |||
== Function == | == Function == |