User:Kerry Frattarola/Sandbox 1: Difference between revisions

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==Structure==

<scene name='74/745991/Crixivan/2'>Crixivan</scene>, also known as [[Indinavir]], is an antiviral compound that acts as a protease inhibitor. The <scene name='74/745991/Crixivan/2'>structure</scene> has a molecular weight of 711.875 g/mol and is very soluble in water and ethanol.<ref>Physicians Desk Reference 66th ed. PDR Network, LLC, Montvale, NJ. p. 2086 (2012)</ref> Crixivan works by specifically binding to the HIV-1 protease active site by mimicking a target substrate protein and essentially becoming “stuck” in the enzyme active site, disabling the enzyme. The pyridine ring on Crixivan ~~interacts with Arg8 in~~ the ~~protease to conform~~ to the active site. ~~When the HIV-1 protease attacks the~~ hydroxyethylene group ~~of the molecule, the bond does not lyse due to~~ the molecule~~'s stability~~.

<scene name='74/745991/Crixivan/2'>Crixivan</scene>, also known as [[Indinavir]], is an antiviral compound that acts as a protease inhibitor. The <scene name='74/745991/Crixivan/2'>structure</scene> has a molecular weight of 711.875 g/mol and is very soluble in water and ethanol.<ref>Physicians Desk Reference 66th ed. PDR Network, LLC, Montvale, NJ. p. 2086 (2012)</ref> Crixivan works by specifically binding to the HIV-1 protease active site by mimicking a target substrate protein and essentially becoming “stuck” in the enzyme active site, disabling the enzyme. The pyridine ring on Crixivan conforms the molecule to the active site. The hydroxyethylene group stabilizes the molecule and prevents lysis.

== Function ==

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 ==Structure==
-<scene name='74/745991/Crixivan/2'>Crixivan</scene>, also known as [[Indinavir]], is an antiviral compound that acts as a protease inhibitor. The <scene name='74/745991/Crixivan/2'>structure</scene> has a molecular weight of 711.875 g/mol and is very soluble in water and ethanol.<ref>Physicians Desk Reference 66th ed. PDR Network, LLC, Montvale, NJ. p. 2086 (2012)</ref> Crixivan works by specifically binding to the HIV-1 protease active site by mimicking a target substrate protein and essentially becoming “stuck” in the enzyme active site, disabling the enzyme. The pyridine ring on Crixivan interacts with Arg8 in the protease to conform to the active site. When the HIV-1 protease attacks the hydroxyethylene group of the molecule, the bond does not lyse due to the molecule's stability.
+<scene name='74/745991/Crixivan/2'>Crixivan</scene>, also known as [[Indinavir]], is an antiviral compound that acts as a protease inhibitor. The <scene name='74/745991/Crixivan/2'>structure</scene> has a molecular weight of 711.875 g/mol and is very soluble in water and ethanol.<ref>Physicians Desk Reference 66th ed. PDR Network, LLC, Montvale, NJ. p. 2086 (2012)</ref> Crixivan works by specifically binding to the HIV-1 protease active site by mimicking a target substrate protein and essentially becoming “stuck” in the enzyme active site, disabling the enzyme. The pyridine ring on Crixivan conforms the molecule to the active site. The hydroxyethylene group stabilizes the molecule and prevents lysis.
 == Function ==