Subtilisin: Difference between revisions

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<StructureSection load='2sic' size='450' side='right' caption='Subtilisin (deepskyblue) complex with streptomycin inhibitor (green) and Ca+2 ions (green) (PDB entry [[2sic]])' scene='43/430882/Cv/2'>
<StructureSection load='2sic' size='350' side='right' caption='Subtilisin (deepskyblue) complex with streptomycin inhibitor (green) and Ca+2 ions (green) (PDB entry [[2sic]])' scene='43/430882/Cv/2'>
== Function ==
== Function ==
[[Subtilisin]] is a serine protease.  A 77 amino acid propeptide is cleaved from the N-terminus of pro-Sub to create the mature active enzym<ref>PMID:4967581</ref>.  See detalis in [[User:Tommie Hata/Introduction to Protein Engineering-Subtilisin]].
[[Subtilisin]] is a serine protease.  A 77 amino acid propeptide is cleaved from the N-terminus of pro-Sub to create the mature active enzym<ref>PMID:4967581</ref>.  See detalis in [[User:Tommie Hata/Introduction to Protein Engineering-Subtilisin]].
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**[[1r0r]] – BsSub+ovomucoid<br />
**[[1r0r]] – BsSub+ovomucoid<br />
**[[1oyv]] – BsSub+tomato inhibitor II<br />
**[[1oyv]] – BsSub+tomato inhibitor II<br />
**[[1sbn]], [[1sib]], [[2sec]], [[1sni]], [[1cse]] – BsSub+Elgin C<br />
**[[1sbn]], [[1sib]], [[2sec]], [[1cse]] – BsSub+Elgin C<br />
**[[2sni]] - BaSub+Elgin C2 <br />
**[[2sni]] - BaSub+Elgin C2 <br />
**[[1mee]] - BpSub+Elgin C – ''Bacillus pumilus''
**[[1mee]] - BpSub+Elgin C – ''Bacillus pumilus''

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Alexander Berchansky, Michal Harel, Joel L. Sussman