5fdx: Difference between revisions

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'''Unreleased structure'''


The entry 5fdx is ON HOLD  until Paper Publication
==Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.==
 
<StructureSection load='5fdx' size='340' side='right' caption='[[5fdx]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
Authors: BARTUAL, S.G., PINKAS, D.M., WANG, Z., DING, K., Mahajan, P., KUPINSKA, K., Mukhopadhyay, S., Strain-Damerell, C., Chalk, R., Borkowska, O., Talon, R., Kopec, J., Williams, E., Tallant, C., Chaikuad, A., Sorell, F., Newman, J., Burgess-Brown, N., VON DELFT, F., Arrowsmith, C.H., Edwards, A.M., BOUNTRA, C., BULLOCK, A., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5fdx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FDX FirstGlance]. <br>
Description: Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5X1:3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-~{N}-[(4~{R})-4-METHYL-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLIN-7-YL]-5-(TRIFLUOROMETHYL)BENZAMIDE'>5X1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
[[Category: Bullock, A]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdx OCA], [http://pdbe.org/5fdx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fdx RCSB], [http://www.ebi.ac.uk/pdbsum/5fdx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fdx ProSAT]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Arrowsmith, C H]]
[[Category: BARTUAL, S G]]
[[Category: BOUNTRA, C]]
[[Category: BULLOCK, A]]
[[Category: Borkowska, O]]
[[Category: Burgess-Brown, N]]
[[Category: Chaikuad, A]]
[[Category: Chaikuad, A]]
[[Category: Sorell, F]]
[[Category: Burgess-Brown, N]]
[[Category: Borkowska, O]]
[[Category: Pinkas, D.M]]
[[Category: Newman, J]]
[[Category: Mukhopadhyay, S]]
[[Category: Ding, K]]
[[Category: Wang, Z]]
[[Category: Bountra, C]]
[[Category: Bartual, S.G]]
[[Category: Kupinska, K]]
[[Category: Arrowsmith, C.H]]
[[Category: Chalk, R]]
[[Category: Chalk, R]]
[[Category: Williams, E]]
[[Category: DELFT, F VON]]
[[Category: DING, K]]
[[Category: Edwards, A M]]
[[Category: KUPINSKA, K]]
[[Category: Kopec, J]]
[[Category: Kopec, J]]
[[Category: Von Delft, F]]
[[Category: Mahajan, P]]
[[Category: Mahajan, P]]
[[Category: Edwards, A.M]]
[[Category: Mukhopadhyay, S]]
[[Category: Newman, J]]
[[Category: PINKAS, D M]]
[[Category: Structural genomic]]
[[Category: Sorell, F]]
[[Category: Strain-Damerell, C]]
[[Category: Tallant, C]]
[[Category: Talon, R]]
[[Category: Talon, R]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: WANG, Z]]
[[Category: Tallant, C]]
[[Category: Williams, E]]
[[Category: Strain-Damerell, C]]
[[Category: Ddr1 kinase]]
[[Category: Inhibitor]]
[[Category: Psi-biology]]
[[Category: Sgc]]
[[Category: Transferase]]

Revision as of 21:41, 26 October 2016

Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.

Structural highlights

5fdx is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Activity:Receptor protein-tyrosine kinase, with EC number 2.7.10.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

5fdx, resolution 2.65Å

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OCA
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