5eys: Difference between revisions

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-'''Unreleased structure'''
-The entry 5eys is ON HOLD
+==Crystal structure of murine neuroglobin mutant F106W at ambient pressure==
+<StructureSection load='5eys' size='340' side='right' caption='[[5eys]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
-Authors: Colloc'h, N., Girard, E., Vallone, B., Prange, T.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5eys]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EYS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EYS FirstGlance]. <br>
-Description: Crystal structure of murine neuroglobin mutant F106W at ambient pressure
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5eet|5eet]]</td></tr>
-[[Category: Colloc'H, N]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eys FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eys OCA], [http://pdbe.org/5eys PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eys RCSB], [http://www.ebi.ac.uk/pdbsum/5eys PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eys ProSAT]</span></td></tr>
-[[Category: Vallone, B]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/NGB_MOUSE NGB_MOUSE]] Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.<ref>PMID:11473111</ref> <ref>PMID:11473128</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Girard, E]]
 [[Category: Prange, T]]
+[[Category: Vallone, B]]
+[[Category: H, N Colloc]]
+[[Category: Globin]]
+[[Category: Oxygen storage-transporter]]
+[[Category: Transport protein]]