5k24: Difference between revisions

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-'''Unreleased structure'''
-The entry 5k24 is ON HOLD  until Paper Publication
+==Crystal structure of the complex between phosphatase PRL-2 in the oxidized state with the Bateman domain of murine magnesium transporter CNNM3==
+<StructureSection load='5k24' size='340' side='right' caption='[[5k24]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5k24]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5K24 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5k22|5k22]], [[5k23|5k23]], [[5k25|5k25]]</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5k24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k24 OCA], [http://pdbe.org/5k24 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5k24 RCSB], [http://www.ebi.ac.uk/pdbsum/5k24 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5k24 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TP4A2_MOUSE TP4A2_MOUSE]] Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB (By similarity). [[http://www.uniprot.org/uniprot/CNNM3_MOUSE CNNM3_MOUSE]] Probable metal transporter.
+__TOC__
+</StructureSection>
+[[Category: Protein-tyrosine-phosphatase]]
+[[Category: Gehring, K]]
+[[Category: Gulerez, I]]
+[[Category: Kozlov, G]]
+[[Category: Complex]]
+[[Category: Hydrolase]]
+[[Category: Hydrolase-transporter protein-protein binding complex]]
+[[Category: Magnesium transporter]]
+[[Category: Phosphatase]]
+[[Category: Protein binding]]