5kar: Difference between revisions

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-'''Unreleased structure'''
-The entry 5kar is ON HOLD  until Paper Publication
+==Murine acid sphingomyelinase-like phosphodiesterase 3b (SMPDL3B)==
+<StructureSection load='5kar' size='340' side='right' caption='[[5kar]], [[Resolution|resolution]] 1.14&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5kar]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KAR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KAR FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kas|5kas]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kar FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kar OCA], [http://pdbe.org/5kar PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kar RCSB], [http://www.ebi.ac.uk/pdbsum/5kar PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kar ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/ASM3B_MOUSE ASM3B_MOUSE]] Lipid-modulating phosphodiesterase. Active on the surface of macrophages and dendritic cells and strongly influences macrophage lipid composition and membrane fluidity. Acts as a negative regulator of Toll-like receptor signaling (PubMed:26095358).<ref>PMID:26095358</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Gorelik, A]]
+[[Category: Heinz, L X]]
+[[Category: Illes, K]]
+[[Category: Nagar, B]]
+[[Category: Superti-Furga, G]]
+[[Category: Extracellular]]
+[[Category: Hydrolase]]
+[[Category: Membrane]]
+[[Category: Phosphoesterase]]