CRISPR-Cas9: Difference between revisions

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===Structure of the Cas7 subunit.===
===Structure of the Cas7 subunit.===
<scene name='74/742625/Cv/16'>Rocket representation of Cas7 colored by domain: thumb (green), fingers (blue), and palm (purple).</scene> The filament is arranged such that the <scene name='74/742625/Cv/17'>thumb of one Cas7 subunit, composed of an extended β hairpin, extends toward the fingers of the adjacent subunit</scene>. <scene name='74/742625/Cv/18'>90° rotation about axis Z</scene>.
 
Within Cascade, the <scene name='74/742625/Cv/19'>six Cas7 subunits form a right-handed filament</scene>, with a pitch of ~135Å, around the guide target hybrid. <scene name='74/742625/Cv/16'>Rocket representation of one Cas7 colored by domain: thumb (green), fingers (blue), and palm (purple).</scene> The filament is arranged such that the <scene name='74/742625/Cv/17'>thumb of one Cas7 subunit, composed of an extended β hairpin, extends toward the fingers of the adjacent subunit</scene>. <scene name='74/742625/Cv/18'>90° rotation about axis Z</scene>.
</StructureSection>
</StructureSection>
== References ==
== References ==
<references/>
<references/>

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Alexander Berchansky, Michal Harel