Tissue factor: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 3: | Line 3: | ||
== Function == | == Function == | ||
'''Tissue factor''' (TF) is a high-affinity receptor for the blood coagulation factor VII. The TF/factor VII complex is responsible for the initiation of the coagulation protease cascade. | '''Tissue factor''' (TF) is a high-affinity receptor for the blood coagulation factor VII. The TF/factor VII complex is responsible for the initiation of the coagulation protease cascade<ref>PMID:23809131</ref>. | ||
== Disease == | == Disease == | ||
TF is involved in cancer angiogenesis and metastasis<ref>PMID:14614019</ref>. | |||
== Relevance == | == Relevance == | ||
TF expression by cardiac myocytes is important to maintain heart hemostasis under normal and pathologic conditions<ref>PMID:17663739</ref>. | |||
== Structural highlights == | == Structural highlights == | ||