Tetherin: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
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The tetherin protein is always found on the surface of B lymphocytes, dendritic cells, and activated T lymphocytes. In brain, kidney, liver, skeletal muscle, pancreas and heart cells. The tetherin gene can be stimulated to be expressed by the production of alpha Interferon, a cytokine. | The tetherin protein is always found on the surface of B lymphocytes, dendritic cells, and activated T lymphocytes. In brain, kidney, liver, skeletal muscle, pancreas and heart cells. The tetherin gene can be stimulated to be expressed by the production of alpha Interferon, a cytokine. | ||
While tetherin may be an effective inhibitor of some viruses, other viruses have been shown to produce viral proteins that downregulate the production and expression of some cellular proteins, including tetherin. Some strains of HIV-1 as well as Ebola viral particles produce viral proteins shown to | While tetherin may be an effective inhibitor of some viruses, other viruses have been shown to produce viral proteins that downregulate the production and expression of some cellular proteins, including tetherin. Some strains of HIV-1 as well as Ebola viral particles produce viral proteins shown to downregulate tetherin expression on the surface of the cell membrane. | ||
==Additional Resources== | ==Additional Resources== | ||