Spermidine Synthase: Difference between revisions
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<StructureSection load='3c6k' size='350' side='right' caption='Structure of human spermidine synthase complex with spermidine and deoxymethyladenosine (PDB entry [[3c6k]])' scene=''> | <StructureSection load='3c6k' size='350' side='right' caption='Structure of human spermidine synthase complex with spermidine and deoxymethyladenosine (PDB entry [[3c6k]])' scene=''> | ||
<font color='red'><b>Under construction!</b></font><br /> | <font color='red'><b>Under construction!</b></font><br /> | ||
== Function == | == Function == | ||
Polyamines are essential in all branches of life. '''Spermidine synthase''' (putrescine aminopropyltransferase, PAPT) (SPS) catalyzes the biosynthesis of spermidine, a ubiquitous polyamine. | Polyamines are essential in all branches of life. '''Spermidine synthase''' (putrescine aminopropyltransferase, PAPT) (SPS) catalyzes the biosynthesis of spermidine, a ubiquitous polyamine<ref>PMID:17585781</ref>. | ||
[[1inl]] - The crystal structure of the PAPT from ''Thermotoga maritima'' (TmPAPT) has been solved to 1.5 A resolution. | [[1inl]] - The crystal structure of the PAPT from ''Thermotoga maritima'' (TmPAPT) has been solved to 1.5 A resolution. | ||
The structure of TmPAPT in a complex with adoDATO ([[1jq3]]) can also be found on this site. | The structure of TmPAPT in a complex with adoDATO ([[1jq3]]) can also be found on this site. | ||
==Structural highlights == | ==Structural highlights == | ||
SPS active sited contains the substrate | SPS active sited contains the substrate spermidine<ref>PMID:18367445</ref>. | ||
</StructureSection> | </StructureSection> | ||
==3D structures of spermidine synthase== | ==3D structures of spermidine synthase== | ||