Severin: Difference between revisions
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{{STRUCTURE_1svy| PDB=1svy | SCENE= |CAPTION=Severin domain 2 complex with Ca+2 (green) and Na+ (purple) ions [[1svy]] }} | {{STRUCTURE_1svy| PDB=1svy | SCENE= |CAPTION=Severin domain 2 complex with Ca+2 (green) and Na+ (purple) ions [[1svy]] }} | ||
[[Severin]] is a calcium-activated protein which binds actin | [[Severin]] is a calcium-activated protein which binds actin. It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins<ref>PMID:15060630</ref>. It is named Adseverin and Scinderin as well. | ||
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[[1svy]] – DdSeverin domain 2 – ''Dictyostelium discoideum'' <br /> | [[1svy]] – DdSeverin domain 2 – ''Dictyostelium discoideum'' <br /> | ||
[[1svq]], [[1svr]] - DdSeverin domain 2 - NMR<br /> | [[1svq]], [[1svr]] - DdSeverin domain 2 - NMR<br /> | ||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 12:52, 28 August 2016
Severin is a calcium-activated protein which binds actin. It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins[1]. It is named Adseverin and Scinderin as well.
3D Structures of Severin3D Structures of Severin
3fg6 – Adseverin C-terminal – human
1svy – DdSeverin domain 2 – Dictyostelium discoideum
1svq, 1svr - DdSeverin domain 2 - NMR
ReferencesReferences
- ↑ Summerscales J, Dawson JF. Probing Dictyostelium severin structure and function by cross linking to actin. Biochem Cell Biol. 2004 Apr;82(2):343-50. PMID:15060630 doi:http://dx.doi.org/10.1139/o04-002