Phosphoglycerate dehydrogenase: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='3ddn' size='450' side='right' caption='Phosphoglycerate dehydrogenase | <StructureSection load='3ddn' size='450' side='right' caption='Phosphoglycerate dehydrogenase complex with hydroxypyruvic acid phosphate and tartarate (PDB entry [[3ddn]])' scene='49/491889/Cv/1'> | ||
== Function == | == Function == | ||
| Line 8: | Line 8: | ||
== Structural highlights == | == Structural highlights == | ||
The active site of ''Mycobacterium tuberculosis'' located in the cleft between the substrate and the NAD-binding domains contains the catalytic dyad Glu:His and the substrate<ref>PMID:18627175</ref>. | The active site of ''Mycobacterium tuberculosis'' PGDH located in the cleft between the substrate and the NAD-binding domains contains the catalytic dyad Glu:His and the substrate<ref>PMID:18627175</ref>. | ||
See [[Rossmann fold]]. | See [[Rossmann fold]]. | ||