Riboswitch: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
Atomic-resolution structures of riboswitch binding sites show that they make numerous hydrogen bonds with their ligands, forming contacts that stabilize RNA interactions to further increase affinity. Some binding sites form pockets that entirely engulf the ligand, and in these instances an induced-fit mechanism of binding must occur. The riboswitch-adenine complex shows the stacking interactions of the zippered-up junctional bubble which is formed by the adenine<ref>PMID:15610857</ref>. | Atomic-resolution structures of riboswitch binding sites show that they make numerous hydrogen bonds with their ligands, forming contacts that stabilize RNA interactions to further increase affinity. Some binding sites form pockets that entirely engulf the ligand, and in these instances an induced-fit mechanism of binding must occur. The <scene name='47/479252/Cv/3'>riboswitch-adenine complex shows the stacking interactions of the zippered-up junctional bubble which is formed by the adenine</scene><ref>PMID:15610857</ref>. | ||
</StructureSection> | </StructureSection> | ||
==3D structures of riboswitch== | ==3D structures of riboswitch== | ||