4mlh: Difference between revisions
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==Human Glucokinase in Complex with a Novel Amino Thiazole Allosteric Activator== | ==Human Glucokinase in Complex with a Novel Amino Thiazole Allosteric Activator== | ||
<StructureSection load='4mlh' size='340' side='right' caption='[[4mlh]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='4mlh' size='340' side='right' caption='[[4mlh]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4mlh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4mlh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MLH FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=VO2:3-(BENZYLOXY)-5-METHYL-N-(4-METHYL-1,3-THIAZOL-2-YL)PYRIDIN-2-AMINE'>VO2</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=VO2:3-(BENZYLOXY)-5-METHYL-N-(4-METHYL-1,3-THIAZOL-2-YL)PYRIDIN-2-AMINE'>VO2</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mle|4mle]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mle|4mle]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GCK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GCK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mlh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mlh RCSB], [http://www.ebi.ac.uk/pdbsum/4mlh PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mlh OCA], [http://pdbe.org/4mlh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mlh RCSB], [http://www.ebi.ac.uk/pdbsum/4mlh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mlh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4mlh" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Glucokinase]] | [[Category: Glucokinase]] | ||
[[Category: | [[Category: Human]] | ||
[[Category: Voegtli, W C]] | [[Category: Voegtli, W C]] | ||
[[Category: Allosteric activator]] | [[Category: Allosteric activator]] |