4tpw: Difference between revisions
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==The co-complex structure of the translation initiation factor eIF4E with the inhibitor 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G== | ==The co-complex structure of the translation initiation factor eIF4E with the inhibitor 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G== | ||
<StructureSection load='4tpw' size='340' side='right' caption='[[4tpw]], [[Resolution|resolution]] 1.50Å' scene=''> | <StructureSection load='4tpw' size='340' side='right' caption='[[4tpw]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
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<table><tr><td colspan='2'>[[4tpw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TPW FirstGlance]. <br> | <table><tr><td colspan='2'>[[4tpw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TPW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TPW FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=33R:(2E)-2-{2-[4-(3,4-DICHLOROPHENYL)-1,3-THIAZOL-2-YL]HYDRAZINYLIDENE}-3-(2-NITROPHENYL)PROPANOIC+ACID'>33R</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MGP:7-METHYL-GUANOSINE-5-TRIPHOSPHATE'>MGP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=33R:(2E)-2-{2-[4-(3,4-DICHLOROPHENYL)-1,3-THIAZOL-2-YL]HYDRAZINYLIDENE}-3-(2-NITROPHENYL)PROPANOIC+ACID'>33R</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MGP:7-METHYL-GUANOSINE-5-TRIPHOSPHATE'>MGP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tpw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tpw RCSB], [http://www.ebi.ac.uk/pdbsum/4tpw PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tpw OCA], [http://pdbe.org/4tpw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tpw RCSB], [http://www.ebi.ac.uk/pdbsum/4tpw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tpw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4tpw" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Eukaryotic initiation factor|Eukaryotic initiation factor]] | |||
== References == | == References == | ||
<references/> | <references/> | ||