4dl6: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
==Human DNA polymerase eta extending primer immediately after cisplatin crosslink (Pt-GG3).==
==Human DNA polymerase eta extending primer immediately after cisplatin crosslink (Pt-GG3).==
<StructureSection load='4dl6' size='340' side='right' caption='[[4dl6]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4dl6' size='340' side='right' caption='[[4dl6]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4dl6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DL6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4dl6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DL6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=XG4:2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]AMINO}PHOSPHORYL]GUANOSINE'>XG4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CPT:CISPLATIN'>CPT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=XG4:2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]AMINO}PHOSPHORYL]GUANOSINE'>XG4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3mr2|3mr2]], [[3mr3|3mr3]], [[3mr5|3mr5]], [[3mr6|3mr6]], [[3si8|3si8]], [[4dl2|4dl2]], [[4dl3|4dl3]], [[4dl4|4dl4]], [[4dl5|4dl5]], [[4dl7|4dl7]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3mr2|3mr2]], [[3mr3|3mr3]], [[3mr5|3mr5]], [[3mr6|3mr6]], [[3si8|3si8]], [[4dl2|4dl2]], [[4dl3|4dl3]], [[4dl4|4dl4]], [[4dl5|4dl5]], [[4dl7|4dl7]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">POLH, RAD30, RAD30A, XPV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">POLH, RAD30, RAD30A, XPV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dl6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dl6 RCSB], [http://www.ebi.ac.uk/pdbsum/4dl6 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dl6 OCA], [http://pdbe.org/4dl6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dl6 RCSB], [http://www.ebi.ac.uk/pdbsum/4dl6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dl6 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
Line 21: Line 22:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4dl6" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
Line 29: Line 31:
</StructureSection>
</StructureSection>
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Biertumpfel, C]]
[[Category: Biertumpfel, C]]
[[Category: Gregory, M]]
[[Category: Gregory, M]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA