5d1q: Difference between revisions
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==IsdB NEAT2 bound by clone D2-06== | |||
<StructureSection load='5d1q' size='340' side='right' caption='[[5d1q]], [[Resolution|resolution]] 3.22Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5d1q]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D1Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5D1Q FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5d1z|5d1z]], [[5d1x|5d1x]]</td></tr> | |||
[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5d1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d1q OCA], [http://pdbe.org/5d1q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5d1q RCSB], [http://www.ebi.ac.uk/pdbsum/5d1q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5d1q ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ISDB_STAAB ISDB_STAAB]] Seems to function as the primary receptor for hemoglobin since its inactivation inhibits the ability of S.aureus to bind hemoglobin. Binds hemoglobin in a dose-dependent way. Required for S.aureus growth using hemoglobin as the sole iron source. Also required for virulence. IsdA and/or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Deng, X]] | [[Category: Deng, X]] | ||
[[Category: Germline encoded]] | |||
[[Category: Igvh1-69]] | |||
[[Category: Immune system]] | |||
[[Category: Isdb neat2]] | |||
Revision as of 19:21, 10 August 2016
IsdB NEAT2 bound by clone D2-06IsdB NEAT2 bound by clone D2-06
Structural highlights
Function[ISDB_STAAB] Seems to function as the primary receptor for hemoglobin since its inactivation inhibits the ability of S.aureus to bind hemoglobin. Binds hemoglobin in a dose-dependent way. Required for S.aureus growth using hemoglobin as the sole iron source. Also required for virulence. IsdA and/or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity). |
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