Fadel A. Samatey Group: Difference between revisions

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Revision as of 22:20, 6 August 2016 view source Eric Martz (talk \| contribs) ConfirmAccount, Editor, Tester, Administrators 27,351 edits →‎Contributions from OIST ← Older edit		Revision as of 15:26, 10 August 2016 view source Fadel A. Samatey (talk \| contribs) 89 edits →‎Contributions from OIST Newer edit →
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	<ref group="xtra">PMID: 25201947</ref><references group="xtra" />		<ref group="xtra">PMID: 25201947</ref><references group="xtra" />

			:<table style="background: #d0ffd0;padding: 6px;"><tr><td>Deletion of the fliO gene creates a mutant strain that is poorly motile; however, suppressor mutations in the fliP gene can partially rescue motility. Here we found a missense mutation that localized to the clpP gene, which encodes the ClpP subunit of the ClpXP protease, and a synonymous mutation that localized to the fliA gene, which encodes the flagellar sigma factor, σ(28) also could partially rescue motility of fliO mutant strains. Combining these suppressor mutations with mutations in the fliP gene fully rescued flagellar biosynthesis and motility for fliO deletion mutant strains. The suppressor mutations in the fliP gene had the greatest effect. This suggests that the function of FliO is closely associated with regulation of FliP during assembly of the flagellum.</td></tr></table>