2v1z: Difference between revisions

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 ==STRUCTURE OF A TEM-1 BETA-LACTAMASE INSERTANT ALLOSTERICALLY REGULATED BY KANAMYCIN AND ANIONS.==
 <StructureSection load='2v1z' size='340' side='right' caption='[[2v1z]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2v1z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V1Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V1Z FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2v1z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V1Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V1Z FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1axb|1axb]], [[1bt5|1bt5]], [[1btl|1btl]], [[1ck3|1ck3]], [[1erm|1erm]], [[1ero|1ero]], [[1erq|1erq]], [[1esu|1esu]], [[1fqg|1fqg]], [[1jtd|1jtd]], [[1jtg|1jtg]], [[1jvj|1jvj]], [[1jwp|1jwp]], [[1jwv|1jwv]], [[1jwz|1jwz]], [[1lhy|1lhy]], [[1li0|1li0]], [[1li9|1li9]], [[1m40|1m40]], [[1nxy|1nxy]], [[1ny0|1ny0]], [[1nym|1nym]], [[1nyy|1nyy]], [[1pzo|1pzo]], [[1pzp|1pzp]], [[1s0w|1s0w]], [[1tem|1tem]], [[1xpb|1xpb]], [[1xxm|1xxm]], [[1yt4|1yt4]], [[1zg4|1zg4]], [[1zg6|1zg6]]</td></tr>
 <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v1z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2v1z RCSB], [http://www.ebi.ac.uk/pdbsum/2v1z PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v1z OCA], [http://pdbe.org/2v1z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v1z RCSB], [http://www.ebi.ac.uk/pdbsum/2v1z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v1z ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/BLAT_ECOLI BLAT_ECOLI]] TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lactamase inhibitors.
+[[http://www.uniprot.org/uniprot/BLAT_ECOLX BLAT_ECOLX]] TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lactamase inhibitors.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v1z ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
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 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 2v1z" style="background-color:#fffaf0;"></div>
 ==See Also==
@@ Line 35: / Line 37: @@
 __TOC__
 </StructureSection>
+[[Category: Bacillus coli migula 1895]]
 [[Category: Beta-lactamase]]
-[[Category: Escherichia coli]]
 [[Category: Barrios, H]]
 [[Category: Declercq, J P]]