4bhw: Difference between revisions
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==Structural basis for autoinhibition of the acetyltransferase activity of p300== | ==Structural basis for autoinhibition of the acetyltransferase activity of p300== | ||
<StructureSection load='4bhw' size='340' side='right' caption='[[4bhw]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='4bhw' size='340' side='right' caption='[[4bhw]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4bhw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4bhw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BHW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BHW FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=01K:[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL+(3R,20R)-20-CARBAMOYL-3-HYDROXY-2,2-DIMETHYL-4,8,14,22-TETRAOXO-12-THIA-5,9,15,21-TETRAAZATRICOS-1-YL+DIHYDROGEN+DIPHOSPHATE'>01K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=01K:[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL+(3R,20R)-20-CARBAMOYL-3-HYDROXY-2,2-DIMETHYL-4,8,14,22-TETRAOXO-12-THIA-5,9,15,21-TETRAAZATRICOS-1-YL+DIHYDROGEN+DIPHOSPHATE'>01K</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_acetyltransferase Histone acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.48 2.3.1.48] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bhw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bhw RCSB], [http://www.ebi.ac.uk/pdbsum/4bhw PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bhw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bhw OCA], [http://pdbe.org/4bhw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bhw RCSB], [http://www.ebi.ac.uk/pdbsum/4bhw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bhw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4bhw" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Histone acetyltransferase]] | [[Category: Histone acetyltransferase]] | ||
[[Category: | [[Category: Human]] | ||
[[Category: Aguilar-Gurrieri, C]] | [[Category: Aguilar-Gurrieri, C]] | ||
[[Category: Delvecchio, M]] | [[Category: Delvecchio, M]] | ||