4j5v: Difference between revisions

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==Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3==
==Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3==
<StructureSection load='4j5v' size='340' side='right' caption='[[4j5v]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='4j5v' size='340' side='right' caption='[[4j5v]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4j39|4j39]], [[1r9f|1r9f]], [[4e5c|4e5c]], [[4e48|4e48]], [[4e6b|4e6b]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4j39|4j39]], [[1r9f|1r9f]], [[4e5c|4e5c]], [[4e48|4e48]], [[4e6b|4e6b]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ORF4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12145 TBSV])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ORF4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12145 TBSV])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j5v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4j5v RCSB], [http://www.ebi.ac.uk/pdbsum/4j5v PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j5v OCA], [http://pdbe.org/4j5v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j5v RCSB], [http://www.ebi.ac.uk/pdbsum/4j5v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j5v ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 21:50, 5 August 2016

Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3

Structural highlights

4j5v is a 2 chain structure with sequence from Tbsv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:ORF4 (TBSV)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[P19_TBSVK] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).

See Also

4j5v, resolution 2.15Å

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