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==Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP==
==Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP==
<StructureSection load='3n2m' size='340' side='right' caption='[[3n2m]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3n2m' size='340' side='right' caption='[[3n2m]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3n2m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum_3d7 Plasmodium falciparum 3d7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N2M FirstGlance]. <br>
<table><tr><td colspan='2'>[[3n2m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N2M FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FNU:6-AMINO-5-FLUOROURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>FNU</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FNU:6-AMINO-5-FLUOROURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>FNU</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2q8l|2q8l]], [[2q8z|2q8z]], [[2qaf|2qaf]], [[3bar|3bar]], [[3bpw|3bpw]], [[3mwa|3mwa]], [[3n34|3n34]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2q8l|2q8l]], [[2q8z|2q8z]], [[2qaf|2qaf]], [[3bar|3bar]], [[3bpw|3bpw]], [[3mwa|3mwa]], [[3n34|3n34]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gi&#124;9310996, PF10_0225 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 Plasmodium falciparum 3D7])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gi&#124;9310996, PF10_0225 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n2m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n2m RCSB], [http://www.ebi.ac.uk/pdbsum/3n2m PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n2m OCA], [http://pdbe.org/3n2m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3n2m RCSB], [http://www.ebi.ac.uk/pdbsum/3n2m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3n2m ProSAT]</span></td></tr>
</table>
</table>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Plasmodium falciparum 3d7]]
[[Category: Plaf7]]
[[Category: Kotra, L P]]
[[Category: Kotra, L P]]
[[Category: Liu, Y]]
[[Category: Liu, Y]]

Revision as of 15:38, 5 August 2016

Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMPCrystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP

Structural highlights

3n2m is a 2 chain structure with sequence from Plaf7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , ,
Gene:gi|9310996, PF10_0225 (PLAF7)
Activity:Orotidine-5'-phosphate decarboxylase, with EC number 4.1.1.23
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

3n2m, resolution 1.80Å

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OCA
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