1mcp: Difference between revisions

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|PDB= 1mcp |SIZE=350|CAPTION= <scene name='initialview01'>1mcp</scene>, resolution 2.7&Aring;
|PDB= 1mcp |SIZE=350|CAPTION= <scene name='initialview01'>1mcp</scene>, resolution 2.7&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mcp OCA], [http://www.ebi.ac.uk/pdbsum/1mcp PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1mcp RCSB]</span>
}}
}}


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[[Category: Padlan, E A.]]
[[Category: Padlan, E A.]]
[[Category: Satow, Y.]]
[[Category: Satow, Y.]]
[[Category: SO4]]
[[Category: immunoglobulin]]
[[Category: immunoglobulin]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:41:51 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:14:25 2008''

Revision as of 22:14, 30 March 2008

File:1mcp.jpg


PDB ID 1mcp

Drag the structure with the mouse to rotate
, resolution 2.7Å
Ligands:
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



PHOSPHOCHOLINE BINDING IMMUNOGLOBULIN FAB MC/PC603. AN X-RAY DIFFRACTION STUDY AT 2.7 ANGSTROMS


OverviewOverview

The crystal structure of the Fab of McPC603, a phosphocholine-binding mouse myeloma protein, has been refined at 2.7 A resolution by a combination of restrained least-squares refinement and molecular modeling. The overall structure remains as previously reported, with an elbow bend angle between the variable and constant modules of 133 degrees. Some adjustments have been made in the structure of the loops as a result of the refinement. The hypervariable loops are all visible in the electron density map with the exception of three residues in the first hypervariable loop of the light chain. A sulfate ion occupies the site of binding of the phosphate moiety of phosphocholine.

About this StructureAbout this Structure

1MCP is a Protein complex structure of sequences from Mus musculus. Full crystallographic information is available from OCA.

ReferenceReference

Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 A., Satow Y, Cohen GH, Padlan EA, Davies DR, J Mol Biol. 1986 Aug 20;190(4):593-604. PMID:3097327

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