1ljp: Difference between revisions
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|GENE= cin1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4785 Phytophthora cinnamomi]) | |GENE= cin1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4785 Phytophthora cinnamomi]) | ||
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ljp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ljp OCA], [http://www.ebi.ac.uk/pdbsum/1ljp PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ljp RCSB]</span> | |||
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[[Category: sterol carrier protein]] | [[Category: sterol carrier protein]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:03:35 2008'' | ||
Revision as of 22:03, 30 March 2008
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| , resolution 1.80Å | |||||||
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| Gene: | cin1B (Phytophthora cinnamomi) | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal Structure of beta-Cinnamomin Elicitin
OverviewOverview
Phytophthora and Pythium species are among the most aggressive plant pathogens, as they invade many economically important crops and forest trees. They secrete large amounts of 10 kDa proteins called elicitins that can act as elicitors of plant defence mechanisms. These proteins may also induce a hypersensitive response (HR) including plant cell necrosis, with different levels of toxicity depending on their pI. Recent studies showed that elicitins function as sterol carrier proteins. The crystallographic structure of the highly necrotic recombinant beta-cinnamomin (beta-CIN) from Phytophthora cinnamomi has been determined at 1.8 A resolution using the molecular-replacement method. beta-CIN has the same overall structure as beta-cryptogein (beta-CRY), an elicitin secreted by Phytophthora cryptogea, although it shows a different surface electrostatic potential distribution. The protein was expressed in Pichia pastoris and crystallized in the triclinic space group with two monomers in the asymmetric unit. The interface formed by these two monomers resembles that from beta-CRY dimer, although with fewer interactions.
About this StructureAbout this Structure
1LJP is a Single protein structure of sequence from Phytophthora cinnamomi. Full crystallographic information is available from OCA.
ReferenceReference
Structure of beta-cinnamomin, a protein toxic to some plant species., Rodrigues ML, Archer M, Martel P, Jacquet A, Cravador A, Carrondo MA, Acta Crystallogr D Biol Crystallogr. 2002 Aug;58(Pt 8):1314-21. Epub 2002, Jul 20. PMID:12136143
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