4hm4: Difference between revisions

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==Naphthalene 1,2-Dioxygenase bound to indan==
==Naphthalene 1,2-Dioxygenase bound to indan==
<StructureSection load='4hm4' size='340' side='right' caption='[[4hm4]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='4hm4' size='340' side='right' caption='[[4hm4]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4hm4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_sp._c18 Pseudomonas sp. c18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HM4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HM4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4hm4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseu8 Pseu8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HM4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HM4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=16N:2,3-DIHYDRO-1H-INDENE'>16N</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=16N:2,3-DIHYDRO-1H-INDENE'>16N</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hm0|4hm0]], [[4hm2|4hm2]], [[4hm3|4hm3]], [[4hm5|4hm5]], [[4hm6|4hm6]], [[4hm7|4hm7]], [[4hm1|4hm1]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hm0|4hm0]], [[4hm2|4hm2]], [[4hm3|4hm3]], [[4hm5|4hm5]], [[4hm6|4hm6]], [[4hm7|4hm7]], [[4hm1|4hm1]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">doxB, NC_004999.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=69011 Pseudomonas sp. C18]), doxD, NC_004999.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=69011 Pseudomonas sp. C18])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">doxB, NC_004999.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=69011 PSEU8]), doxD, NC_004999.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=69011 PSEU8])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hm4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hm4 RCSB], [http://www.ebi.ac.uk/pdbsum/4hm4 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hm4 OCA], [http://pdbe.org/4hm4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hm4 RCSB], [http://www.ebi.ac.uk/pdbsum/4hm4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hm4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</StructureSection>
</StructureSection>
[[Category: Naphthalene 1,2-dioxygenase]]
[[Category: Naphthalene 1,2-dioxygenase]]
[[Category: Pseudomonas sp. c18]]
[[Category: Pseu8]]
[[Category: Ferraro, D J]]
[[Category: Ferraro, D J]]
[[Category: Ramaswamy, S]]
[[Category: Ramaswamy, S]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

Revision as of 02:06, 5 August 2016

Naphthalene 1,2-Dioxygenase bound to indanNaphthalene 1,2-Dioxygenase bound to indan

Structural highlights

4hm4 is a 2 chain structure with sequence from Pseu8. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , ,
Gene:doxB, NC_004999.1 (PSEU8), doxD, NC_004999.1 (PSEU8)
Activity:Naphthalene 1,2-dioxygenase, with EC number 1.14.12.12
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[NDOB_PSEU8] Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-naphthalene dihydrodiol. [NDOC_PSEU8] Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-naphthalene dihydrodiol. The beta subunit may be responsible for the substrate specificity of the enzyme.

See Also

4hm4, resolution 1.50Å

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OCA