4gb2: Difference between revisions
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==HIV-1 protease (mutant Q7K L33I L63I) in complex with a bicyclic pyrrolidine inhibitor== | ==HIV-1 protease (mutant Q7K L33I L63I) in complex with a bicyclic pyrrolidine inhibitor== | ||
<StructureSection load='4gb2' size='340' side='right' caption='[[4gb2]], [[Resolution|resolution]] 1.79Å' scene=''> | <StructureSection load='4gb2' size='340' side='right' caption='[[4gb2]], [[Resolution|resolution]] 1.79Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4gb2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4gb2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GB2 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0LQ:(4AS,7AS)-1,4-BIS(DIPHENYLMETHYL)HEXAHYDRO-1H-PYRROLO[3,4-B]PYRAZINE-2,3-DIONE'>0LQ</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0LQ:(4AS,7AS)-1,4-BIS(DIPHENYLMETHYL)HEXAHYDRO-1H-PYRROLO[3,4-B]PYRAZINE-2,3-DIONE'>0LQ</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qih|3qih]], [[3qn8|3qn8]], [[3qp0|3qp0]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qih|3qih]], [[3qn8|3qn8]], [[3qp0|3qp0]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11686 | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11686 HIV-1])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gb2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gb2 RCSB], [http://www.ebi.ac.uk/pdbsum/4gb2 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gb2 OCA], [http://pdbe.org/4gb2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gb2 RCSB], [http://www.ebi.ac.uk/pdbsum/4gb2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gb2 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Hiv-1]] | |||
[[Category: Heine, A]] | [[Category: Heine, A]] | ||
[[Category: Klebe, G]] | [[Category: Klebe, G]] |