4lw7: Difference between revisions

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==Crystal structure of the mutant H128S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP==
==Crystal structure of the mutant H128S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP==
<StructureSection load='4lw7' size='340' side='right' caption='[[4lw7]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
<StructureSection load='4lw7' size='340' side='right' caption='[[4lw7]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ltp|3ltp]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ltp|3ltp]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lw7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lw7 RCSB], [http://www.ebi.ac.uk/pdbsum/4lw7 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lw7 OCA], [http://pdbe.org/4lw7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lw7 RCSB], [http://www.ebi.ac.uk/pdbsum/4lw7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lw7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==

Revision as of 16:30, 4 August 2016

Crystal structure of the mutant H128S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMPCrystal structure of the mutant H128S of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP

Structural highlights

4lw7 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:Orotidine-5'-phosphate decarboxylase, with EC number 4.1.1.23
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[PYRF_METTH] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]

4lw7, resolution 1.42Å

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