2xq5: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
==PENTAMERIC LIGAND GATED ION CHANNEL GLIC IN COMPLEX WITH TETRAETHYLARSONIUM (TEAS)== | ==PENTAMERIC LIGAND GATED ION CHANNEL GLIC IN COMPLEX WITH TETRAETHYLARSONIUM (TEAS)== | ||
<StructureSection load='2xq5' size='340' side='right' caption='[[2xq5]], [[Resolution|resolution]] 3.50Å' scene=''> | <StructureSection load='2xq5' size='340' side='right' caption='[[2xq5]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2xq5]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Glovi Glovi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XQ5 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARS:ARSENIC'>ARS</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xqa|2xqa]], [[2xq9|2xq9]], [[2xq7|2xq7]], [[2xq3|2xq3]], [[2xq8|2xq8]], [[2xq4|2xq4]], [[2xq6|2xq6]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xqa|2xqa]], [[2xq9|2xq9]], [[2xq7|2xq7]], [[2xq3|2xq3]], [[2xq8|2xq8]], [[2xq4|2xq4]], [[2xq6|2xq6]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xq5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2xq5 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xq5 OCA], [http://pdbe.org/2xq5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xq5 RCSB], [http://www.ebi.ac.uk/pdbsum/2xq5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xq5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/ | [[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Line 17: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2xq5" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
Line 24: | Line 26: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Glovi]] | ||
[[Category: Bertozzi, C]] | [[Category: Bertozzi, C]] | ||
[[Category: Dutzler, R]] | [[Category: Dutzler, R]] |