4ixg: Difference between revisions
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==pcDHFR-268-K37S-N69F variant== | ==pcDHFR-268-K37S-N69F variant== | ||
<StructureSection load='4ixg' size='340' side='right' caption='[[4ixg]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='4ixg' size='340' side='right' caption='[[4ixg]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ixg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4ixg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pneca Pneca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IXG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IXG FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IXG:N~6~-METHYL-N~6~-PHENYLPYRIDO[2,3-D]PYRIMIDINE-2,4,6-TRIAMINE'>IXG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IXG:N~6~-METHYL-N~6~-PHENYLPYRIDO[2,3-D]PYRIMIDINE-2,4,6-TRIAMINE'>IXG</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ixe|4ixe]], [[4ixf|4ixf]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ixe|4ixe]], [[4ixf|4ixf]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ixg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ixg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ixg RCSB], [http://www.ebi.ac.uk/pdbsum/4ixg PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ixg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ixg OCA], [http://pdbe.org/4ixg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ixg RCSB], [http://www.ebi.ac.uk/pdbsum/4ixg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ixg ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4ixg" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: | [[Category: Pneca]] | ||
[[Category: Cody, V]] | [[Category: Cody, V]] | ||
[[Category: Dihydrofolate reductase inhibitor ternary complex double variant]] | [[Category: Dihydrofolate reductase inhibitor ternary complex double variant]] | ||
[[Category: Oxidoreductase-inhibitor complex]] | [[Category: Oxidoreductase-inhibitor complex]] | ||
[[Category: Reductase]] | [[Category: Reductase]] |