Protein phosphatase: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
<StructureSection load='3k7v' size='400' side='right' scene='' caption='Human PP2A catalytic (pink) and regulatory (grey) subunits complex with tumor-inducing toxin and sulfate [[3k7v]]'> | |||
== Function == | == Function == | ||
'''Protein phosphatases''' (PP) regulate protein phosphorylation and thus are key in intracellular signal transduction processes.<br /> | '''Protein phosphatases''' (PP) regulate protein phosphorylation and thus are key in intracellular signal transduction processes.<br /> | ||
Line 13: | Line 13: | ||
== Structural highlights == | == Structural highlights == | ||
Algal toxin binds at the surface pocket of the PP2A catalytic subunit which contains the Mn+2 ion cofactors<ref>PMID:19916524</ref>. | Algal toxin binds at the surface pocket of the PP2A catalytic subunit which contains the Mn+2 ion cofactors<ref>PMID:19916524</ref>. | ||
</StructureSection> | |||
== 3D Structures of protein phosphatase== | == 3D Structures of protein phosphatase== | ||