Protein phosphatase: Difference between revisions

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{{STRUCTURE_3k7v|  PDB=3k7v | SIZE=400| SCENE= |right|CAPTION=Human PP2A catalytic (pink) and regulatory (grey) subunits complex with tumor-inducing toxin and sulfate [[3k7v]] }}
<StructureSection load='3k7v' size='400' side='right' scene='' caption='Human PP2A catalytic (pink) and regulatory (grey) subunits complex with tumor-inducing toxin and sulfate [[3k7v]]'>
== Function ==
== Function ==
'''Protein phosphatases''' (PP) regulate protein phosphorylation and thus are key in intracellular signal transduction processes.<br />
'''Protein phosphatases''' (PP) regulate protein phosphorylation and thus are key in intracellular signal transduction processes.<br />
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== Structural highlights ==
== Structural highlights ==
Algal toxin binds at the surface pocket of the PP2A catalytic subunit which contains the Mn+2 ion cofactors<ref>PMID:19916524</ref>.
Algal toxin binds at the surface pocket of the PP2A catalytic subunit which contains the Mn+2 ion cofactors<ref>PMID:19916524</ref>.
 
</StructureSection>
== 3D Structures of protein phosphatase==
== 3D Structures of protein phosphatase==
   
   

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Michal Harel, Alexander Berchansky, Joel L. Sussman, Alexsandra Tifane Santos do Nascimento