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==Crystal Structure of the I80Y/L114V/I116V mutant of LEH== | |||
<StructureSection load='5cf2' size='340' side='right' caption='[[5cf2]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5cf2]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CF2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CF2 FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cf1|5cf1]]</td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Limonene-1,2-epoxide_hydrolase Limonene-1,2-epoxide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.2.8 3.3.2.8] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cf2 OCA], [http://pdbe.org/5cf2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cf2 RCSB], [http://www.ebi.ac.uk/pdbsum/5cf2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cf2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/LIMA_RHOER LIMA_RHOER]] Catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. Can use both the (-) and (+) isomers of limonene-1,2-epoxide as substrates and also has some activity with 1-methylcyclohexene oxide, cyclohexene oxide and indene oxide as substrates. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Limonene-1,2-epoxide hydrolase]] | |||
[[Category: Reetz, M T]] | |||
[[Category: Sun, Z T]] | |||
[[Category: Wu, L]] | [[Category: Wu, L]] | ||
[[Category: | [[Category: Zhou, J H]] | ||
[[Category: | [[Category: Epoxide hydrolase]] | ||
[[Category: | [[Category: Hydrolase]] | ||
[[Category: Stereoselective transformation]] | |||
Revision as of 14:42, 14 July 2016
Crystal Structure of the I80Y/L114V/I116V mutant of LEHCrystal Structure of the I80Y/L114V/I116V mutant of LEH
Structural highlights
Function[LIMA_RHOER] Catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. Can use both the (-) and (+) isomers of limonene-1,2-epoxide as substrates and also has some activity with 1-methylcyclohexene oxide, cyclohexene oxide and indene oxide as substrates. |
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