5b42: Difference between revisions
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==Crystal structure of the C-terminal endonuclease domain of Aquifex aeolicus MutL.== | |||
<StructureSection load='5b42' size='340' side='right' caption='[[5b42]], [[Resolution|resolution]] 1.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5b42]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B42 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B42 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b42 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b42 OCA], [http://pdbe.org/5b42 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b42 RCSB], [http://www.ebi.ac.uk/pdbsum/5b42 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b42 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/MUTL_AQUAE MUTL_AQUAE]] This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Baba, S]] | [[Category: Baba, S]] | ||
[[Category: Fukui, K]] | [[Category: Fukui, K]] | ||
[[Category: Kumasaka, T]] | |||
[[Category: Yano, T]] | [[Category: Yano, T]] | ||
[[Category: | [[Category: Cadmium]] | ||
[[Category: Dna binding protein]] | |||
[[Category: Endonuclease]] | |||
[[Category: Mismatch repair]] | |||
Revision as of 14:40, 14 July 2016
Crystal structure of the C-terminal endonuclease domain of Aquifex aeolicus MutL.Crystal structure of the C-terminal endonuclease domain of Aquifex aeolicus MutL.
Structural highlights
Function[MUTL_AQUAE] This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). |
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