Proteasome: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Joel L. Sussman, Jaime Prilusky

Revision as of 13:25, 13 July 2016 view source Michal Harel (talk \| contribs) 31,761 edits No edit summary ← Older edit		Revision as of 13:26, 13 July 2016 view source Michal Harel (talk \| contribs) 31,761 edits No edit summary Newer edit →
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	{{STRUCTURE_3gpt\| PDB=3gpt \| SIZE=400\| SCENE= \|right\|CAPTION=~~Proteasome~~ complex with salinosporamide derivative, [[3gpt]] }}		{{STRUCTURE_3gpt\| PDB=3gpt \| SIZE=400\| SCENE= \|right\|CAPTION=Yeast proteasome 20S core complex with salinosporamide derivative, [[3gpt]] }}

	[[Proteasome]] (PRTS) are large protein complexes which degrade unneeded proteins into small polypeptides<ref>PMID:22350895</ref>. The '''26S PRTS''' is composed of a central '''20S core particle''' which contains 4 stacked rings each with several members and two 19S caps. The core particle two outer rings contain 7 α subunits which form the PRTS gate. The two inner rings contain 6 β subunits with protease activity. The 19S cap is composed of a base with 10 proteins six of which are ATPases and a lid which contains 9 proteins which bind polyubiquitin. <br />		[[Proteasome]] (PRTS) are large protein complexes which degrade unneeded proteins into small polypeptides<ref>PMID:22350895</ref>. The '''26S PRTS''' is composed of a central '''20S core particle''' which contains 4 stacked rings each with several members and two 19S caps. The core particle two outer rings contain 7 α subunits which form the PRTS gate. The two inner rings contain 6 β subunits with protease activity. The 19S cap is composed of a base with 10 proteins six of which are ATPases and a lid which contains 9 proteins which bind polyubiquitin. <br />