Proteasome: Difference between revisions
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{{STRUCTURE_3gpt| PDB=3gpt | SIZE=400| SCENE= |right|CAPTION=Proteasome complex with salinosporamide derivative, [[3gpt]] }} | {{STRUCTURE_3gpt| PDB=3gpt | SIZE=400| SCENE= |right|CAPTION=Proteasome complex with salinosporamide derivative, [[3gpt]] }} | ||
[[Proteasome]] (PRTS) are large protein complexes which degrade unneeded proteins into small polypeptides. The 26S PRTS is composed of a central 20S core particle which contains 4 stacked rings each with several members and two 19S caps. The core particle two outer rings contain 7 α subunits which form the PRTS gate. The two inner rings contain 6 β subunits with protease activity. The 19S cap is composed of a base with 10 proteins six of which are ATPases and a lid which contains 9 proteins which bind polyubiquitin. <br /> | [[Proteasome]] (PRTS) are large protein complexes which degrade unneeded proteins into small polypeptides<ref>PMID:22350895</ref>. The '''26S PRTS''' is composed of a central '''20S core particle''' which contains 4 stacked rings each with several members and two 19S caps. The core particle two outer rings contain 7 α subunits which form the PRTS gate. The two inner rings contain 6 β subunits with protease activity. The 19S cap is composed of a base with 10 proteins six of which are ATPases and a lid which contains 9 proteins which bind polyubiquitin. <br /> | ||
For more details see [[3unb]]. | For more details see [[3unb]]. | ||
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**[[4g4s]] – yPRTS + proteasome assembly chaperon 1 & 2<br /> | **[[4g4s]] – yPRTS + proteasome assembly chaperon 1 & 2<br /> | ||
}} | }} | ||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||