Plasmepsin: Difference between revisions
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Michal Harel (talk | contribs) No edit summary |
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<StructureSection load='4cku' size='350' side='right' caption='Plasmepsin II complex with a potential antimalarial drug (PDB entry [[4cku]])' scene=''> | |||
== Function == | == Function == | ||
[[Plasmepsin]] (Plm) is a hemoglobin-degrading enzyme produced by the plasmodium parasite. It is an aspartic acid protease having 2 aspartic acid residues in the active site. Ten Plm isoforms are known which are named Plm I, II, etc and '''Histo-Aspartic Protease (HAP)'''. | [[Plasmepsin]] (Plm) is a hemoglobin-degrading enzyme produced by the plasmodium parasite. It is an aspartic acid protease having 2 aspartic acid residues in the active site. Ten Plm isoforms are known which are named Plm I, II, etc and '''Histo-Aspartic Protease (HAP)'''. | ||
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==Relevance == | ==Relevance == | ||
Plm is a potential target for anti-malaria drugs<ref>PMID:25719272</ref>. | Plm is a potential target for anti-malaria drugs<ref>PMID:25719272</ref>. | ||
== Structural highlights == | |||
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