Phospholipase A2: Difference between revisions
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*'''PLA2 group XV''' is located in the endocytic system and may be involved in CD1d function<ref>PMID:23943550</ref>. <br /> | *'''PLA2 group XV''' is located in the endocytic system and may be involved in CD1d function<ref>PMID:23943550</ref>. <br /> | ||
*'''PLA2 group XVI''' is adipose-specific<ref>PMID:18614531</ref>. <br /> | *'''PLA2 group XVI''' is adipose-specific<ref>PMID:18614531</ref>. <br /> | ||
*'''Lipoprotein-associated phospholipase A2''' or '''platelet-activating factor acetylhydrolase''' (Lp-PLA2) degrades platelet-activating factor and oxidized phospholipids into inactive metabolites. Platelet-activating factor is a potent phospholipid activator and mediator of inflammation, platelet aggregation and other leukocyte functions. | |||
*'''Bothropstoxin (BTX)''' is PLA2 from the snake ''Bothrops jararacussu''.<br /> | *'''Bothropstoxin (BTX)''' is PLA2 from the snake ''Bothrops jararacussu''.<br /> | ||
*'''Piratoxin (PTX)''' is PLA2 from the snake ''Bothrops piraña''.<br /> | *'''Piratoxin (PTX)''' is PLA2 from the snake ''Bothrops piraña''.<br /> | ||
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**[[1mf4]], [[2rd4]], [[3gci]], [[3jq5]], [[3jql]], [[3jti]] - NnPLA2+polypeptide<br /> | **[[1mf4]], [[2rd4]], [[3gci]], [[3jq5]], [[3jql]], [[3jti]] - NnPLA2+polypeptide<br /> | ||
**[[1skg]], [[1sqz]], [[1tg1]], [[1tj9]], [[1tjk]], [[1tk4]], [[2do2]], [[2g58]], [[2gns]], [[2pb8]] - DrPLA2+polypeptide | **[[1skg]], [[1sqz]], [[1tg1]], [[1tj9]], [[1tjk]], [[1tk4]], [[2do2]], [[2g58]], [[2gns]], [[2pb8]] - DrPLA2+polypeptide | ||
*Lp-PLA2 | |||
**[[1wab]] – bLP-PLA2 + acetate – bovine<br /> | |||
**[[1bwp]], 1bwq]], 1bwr]], 1es9]] – bLP-PLA2 ( mutant) <br /> | |||
**[[1fxw]] – bLP-PLA2 β + γ subunits<br /> | |||
**[[1uuj] - mLP-PLA2 α subunit N terminal – mouse<br /> | |||
**[[1vyh]] - mLP-PLA2 α subunit C terminal + β subunit<br /> | |||
**[[3d59 – hLP-PLA2 residues 47-429 – human<br /> | |||
*Lp-PLA2 binary complexes | |||
**[[3dt6]] - bLP-PLA2 α subunit (mutant) + paraoxon<br /> | |||
**[[3dt8]] - bLP-PLA2 α subunit (mutant) + sarin<br /> | |||
**[[3dt9]] - bLP-PLA2 α subunit (mutant) + soman<br /> | |||
**[[3d5e]] - hLP-PLA2 residues 47-429 + paraoxon<br /> | |||
**[[3f96]] - hLP-PLA2 residues 47-429 + sarin<br /> | |||
**[[3f97]] - hLP-PLA2 residues 47-429 + soman<br /> | |||
**[[3f98]] - hLP-PLA2 residues 47-429 + tabun<br /> | |||
**[[3f9c]] - hLP-PLA2 residues 47-429 + DFP<br /> | |||
**[[5i8p]], [[5i9i]], [[5jad]], [[5jah]], [[5jal]], [[5jan]], [[5jao]], [[5jap]], [[5jar]], [[5jas]], [[5jat]], [[5jau]] - hLP-PLA2 residues 47-429 + inhibitor<br /> | |||
* Bothrops toxins | * Bothrops toxins | ||