Phenylpyruvate decarboxylase: Difference between revisions
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{{STRUCTURE_2q5o| PDB=2q5o | SIZE=400| SCENE= |right|CAPTION=Phenylpyruvate decarboxylase dimer complex with phenylpyruvate, deaza-ThDP and Mg+2 (green) ion [[2q5o]] }} | {{STRUCTURE_2q5o| PDB=2q5o | SIZE=400| SCENE= |right|CAPTION=Phenylpyruvate decarboxylase dimer complex with phenylpyruvate, deaza-ThDP and Mg+2 (green) ion [[2q5o]] }} | ||
== Function == | |||
'''Phenylpyruvate decarboxylase''' (PPDC) catalyzes the conversion of phenylpyruvate to phenylacetaldehyde. PPDC participates in phenylalanine and tryptophan metabolism<ref>PMID:12902239</ref>. PPDC is a thiamine diphosphate (ThDP) (i.e., vitamin B1)-dependent enzyme. | |||
== Structural highlights == | |||
PPDC active site contains the ThDP cofactor and the phenypyruvate substrate<ref>PMID:17905741</ref>. | |||
== 3D Structures of phenylpyruvate decarboxylase == | == 3D Structures of phenylpyruvate decarboxylase == | ||