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==Structure of the DNA-binding domain of Escherichia coli methionine biosynthesis regulator MetR== | |||
<StructureSection load='5fo5' size='340' side='right' caption='[[5fo5]], [[Resolution|resolution]] 2.16Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5fo5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FO5 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fo5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fo5 OCA], [http://pdbe.org/5fo5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fo5 RCSB], [http://www.ebi.ac.uk/pdbsum/5fo5 PDBsum]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/METR_ECOLI METR_ECOLI]] Control of the last step in methionine biosynthesis; MetR is a positive activator of the metA, metE and metH genes. MetR is also a negative regulator of its own expression. Binds homocysteine as an inducer. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Carr, S B]] | |||
[[Category: Phillips, S E]] | |||
[[Category: Porter, J]] | [[Category: Porter, J]] | ||
[[Category: Punekar, A | [[Category: Punekar, A S]] | ||
[[Category: | [[Category: Stauffer, G V]] | ||
[[Category: | [[Category: Urbanowski, M L]] | ||
[[Category: | [[Category: Activator]] | ||
[[Category: Dna-binding]] | |||
[[Category: Hth]] | |||
[[Category: Lysr-type transcriptional regulator]] | |||
[[Category: Methionine biosynthesis]] | |||
[[Category: Repressor]] | |||
[[Category: Transcription]] | |||
[[Category: Transcription regulation]] | |||
Revision as of 18:23, 20 June 2016
Structure of the DNA-binding domain of Escherichia coli methionine biosynthesis regulator MetRStructure of the DNA-binding domain of Escherichia coli methionine biosynthesis regulator MetR
Structural highlights
Function[METR_ECOLI] Control of the last step in methionine biosynthesis; MetR is a positive activator of the metA, metE and metH genes. MetR is also a negative regulator of its own expression. Binds homocysteine as an inducer. |
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