5eow: Difference between revisions

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'''Unreleased structure'''


The entry 5eow is ON HOLD  until Paper Publication
==Crystal Structure of 6-Hydroxynicotinic Acid 3-Monooxygenase from Pseudomonas putida KT2440==
 
<StructureSection load='5eow' size='340' side='right' caption='[[5eow]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
Authors: Yuen, M.E., Zhen, W., Gerwig, T.J., Story, R.W., Kopp, M., Nakamoto, K., Snider, M.J., Hicks, K.A.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5eow]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EOW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EOW FirstGlance]. <br>
Description: Crystal Structure of 6-Hydroxynicotinic Acid 3-Monooxygenase from Pseudomonas putida KT2440
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
[[Category: Zhen, W]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6-hydroxynicotinate_3-monooxygenase 6-hydroxynicotinate 3-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.13.114 1.14.13.114] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eow OCA], [http://pdbe.org/5eow PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eow RCSB], [http://www.ebi.ac.uk/pdbsum/5eow PDBsum]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/6HN3M_PSEPK 6HN3M_PSEPK]] Catalyzes the oxidative decarboxylation of 6-hydroxynicotinic acid to 2,5-dihydroxypyridine in the aerobic nicotinate degradation pathway.<ref>PMID:18678916</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: 6-hydroxynicotinate 3-monooxygenase]]
[[Category: Gerwig, T J]]
[[Category: Hicks, K A]]
[[Category: Kopp, M]]
[[Category: Kopp, M]]
[[Category: Story, R.W]]
[[Category: Hicks, K.A]]
[[Category: Yuen, M.E]]
[[Category: Snider, M.J]]
[[Category: Nakamoto, K]]
[[Category: Nakamoto, K]]
[[Category: Gerwig, T.J]]
[[Category: Snider, M J]]
[[Category: Story, R W]]
[[Category: Yuen, M E]]
[[Category: Zhen, W]]
[[Category: Flavin monooxygenase]]
[[Category: Oxidative decarboxylase]]
[[Category: Oxidoreductase]]

Revision as of 18:22, 20 June 2016

Crystal Structure of 6-Hydroxynicotinic Acid 3-Monooxygenase from Pseudomonas putida KT2440Crystal Structure of 6-Hydroxynicotinic Acid 3-Monooxygenase from Pseudomonas putida KT2440

Structural highlights

5eow is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
NonStd Res:
Activity:6-hydroxynicotinate 3-monooxygenase, with EC number 1.14.13.114
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[6HN3M_PSEPK] Catalyzes the oxidative decarboxylation of 6-hydroxynicotinic acid to 2,5-dihydroxypyridine in the aerobic nicotinate degradation pathway.[1]

References

  1. ↑ Jimenez JI, Canales A, Jimenez-Barbero J, Ginalski K, Rychlewski L, Garcia JL, Diaz E. Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11329-34. doi:, 10.1073/pnas.0802273105. Epub 2008 Aug 4. PMID:18678916 doi:http://dx.doi.org/10.1073/pnas.0802273105

5eow, resolution 2.10Å

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